Osteoporosis

Friday

Genetic Test Shows Risk Of Osteoporosis


E
arly bone loss could be prevented.

Osteoporosis is treacherous. The dreaded bone loss comes slowly and silently, since a long time feels no complaints. Many do so only for measuring bone density when back pain or fractures occur.

But the shrinkage in bone mass and stability can sometimes despite gegensteuernder measures only conditionally halt.

"The dilemma is that both bone density measurement as well as biochemical parameters of bone metabolism show a change only if the bone resorption has already begun," it brings the Vienna orthopedist primarius Alexander force of the Vertebralia day-to the point.

Early knowledge about personal risk of osteoporosis is now shipping a new genetic test (osteoporosis sensor), by current scientific research after inheritance factors for osteoporosis and fracture incidence benefited.

Investigations are very small changes (called polymorphisms) in up to three specific genes (collagen I, alpha-1, vitamin D Rezptor, estrogen receptor alpha).

"They have proved in a series of scientific studies as an important marker for risk of osteoporosis or so correlating risk for osteoporotic fractures are confirmed," says Associate Professor Michael Klentze, a specialist in gynecology from Munich.

Klentze was instrumental in the development of osteoporosis sensor involved. Women, where changes in these three genes are found, more likely to be diagnosed osteoporosis, according to the experts, and have twice as a high risk of fracture of the femoral neck bone expected.