Osteoporosis : Daily Injection For Strong Bones ?

T

he Food and Drug Administration (FDA) has just affix his seal on a few current treatment of osteoporosis.Few current and leaving pensive, since it is a daily injection in the thigh or abdomen….

The Teriparatide, extracted from the parathyroid hormone that regulates calcium levels in the blood, has been tested for 19 months on a cohort of 1 600 and postmenopausal women with osteoporosis.

With good results, as a result of a daily injection bone mineral density measured at vertebral bones and in the basin has been significantly increased after treatment.

This substance would have shown much higher and the treatment received by the control group, and based on a supplemental calcium and vitamin D. A treatment that the state of the art currently is not what is most effective…

However, the effectiveness of Teriparatide being established, its use is permitted today… under control. For it is not devoid of risks.

The FDA cites studies that effect, carried out on rats have shown an increased risk of osteosarcoma, a bone cancer admittedly rare but serious. No cases have been found in humans but the agency stressed that "the risk can not be totally ruled out."

Now whether any patients are ready to make herself each day an injection in the thigh or abdomen.

If the discovery is the delight of researchers who boast the elegance of its mode of action, clinicians them - rheumatologists or general - remain skeptical. We must also say that they are the ones who must care for sick…



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Half Of Transplant Spain Patients Suffer From Osteoporosis

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second patient who underwent organ transplant suffering from osteoporosis in 6 to 12 months after the operation, as highlighted in a recent press release of Roche laboratory-Farma in Spain.

The advanced age, the deficit prior bone mineral density added to the anti-release would be the main osteoporosis risk factors for the development of bone diseases.

As explained by Dr. Jose Maria Campistol of Renal Transplant Unit of the hospital in Barcelona, "once the graft accepted, and the patient's life put out of danger, our concern focuses on improving the quality of life of these people and thus lower risk of osteoporosis "

As such, it is necessary to find new treatments replacing the use of steroids, produces toxic to the bone. Indeed, the use of these steroids is dangerous for bone structure.

They weaken bones and reduce their training. In addition, if the patient does not have a good bone, administration of anti-rejection may cause bone diseases and pathological fractures.

" However, corticosteroids are not solely responsible. Other osteoporosis drugs such inhibitors promote bone imbalances. Indeed, experts have concluded in the necessity of fighting against treatments for osteoporosis patients transplanted.



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Antioxidants : Effective Method Againts Osteoporosis ?

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y reducing the amount of antioxidants present in the bone, lack of estrogen is the main osteoporosis cause, a disease of the bone degeneration, according to a study conducted on rodents by the team headed by Professor Chambers the medical school at Saint Georges Hospital (London), recently published in the Journal of Clinical Investigation.

Professor Chambers and his colleagues in the department of cellular pathology observed that an oophorectomy (removal of the ovaries) the quantity of two major antioxidant present in the bone marrow of mice declined sharply.

The latter would be returned to normal after an injection of estrogen "estradiol 17B."
Moreover, the administration of other antioxidants (N-acetyl-cysteine and ascorbate) promoting the development of the first two cancelled the effects of oophorectomy on bones.

Osteoporosis was recently ranked second in its list of major health problems by the World Health Organization (WHO). The researchers believe that other studies have come to confirm their results before that postmenopausal women, particularly affected by this disease, did throw on nutritional supplements (NAC) or vitamin C (ascorbate).



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Against Osteoporosis : Not Doing Anything

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f the systematic use of hormone replacement therapy (HRT) seems more topical in the aftermath of menopause, the self is not without risk neither. Some plants such as soybeans, are sometimes dangerous.

Menopause is not a disease, of course. This new stage of your life is accompanied by a real physiological changes, which contributes to osteoporosis symptoms.

What is it? From an imbalance in the renewal of your bone cells, which are deteriorating more than they regenerate. Silencieusement without any pain or other signs predictive, your bones become more porous, more fragile and therefore more brittle.

"Wrists broken vertebrae of settlement are common," warns Dr. Marie-Aline Limouzin-Lamothe, a gynecologist in Paris. Just as fractures hip in the elderly. Other fractures are more unexpected, such as those of the ankle or the collarbone. But they are very evocative. "
What has weapons there to fight against these diseases ? Recently, several studies have cautioned against the widespread use of HRT, previously recognized as the best preventive osteoporosis treatments that accompany this period of life.

At the outset, thousands of women in France have decided to stop their osteoporosis treatment.

Some have refused to take any other treatment, others have turned to alternative osteoporosis drugs. "A self should now channel, while 60% to 70% of women have used medicinal plants after they stop their HRT," complains Dr. Serge Rafal, a general practitioner in Paris.

"A diet rich in fruits and vegetables is very important. But soy for example, whose virtues are often vantées against hot flushes, also has a deleterious action on the breast. Abuse is potentially dangerous. Hence l 'Interest to talk to his doctor. Its role is crucial for not doing anything. "