S
ome chemotherapy for breast cancer cause rapid bone loss and sometimes considerable.Dr. Charles Shapiro and his team of University Medical Center in Ohio, just published in The Journal of Clinical Oncology a study which makes virtually chemotherapy in these osteoporosis risk factors…
They followed 49 post-menopausal women not treated for breast cancer in phase I or II, ie fairly early.
Evaluating regular bone mineral density (BMD) of these patients - in 4 weeks, 6 months and one year of treatment - the authors noted that after one year, ovarian function had ceased at 71% of them . With the consequent emergence of the usual changes after menopause.
This development was certainly expected… but the authors were surprised by its proportions. In all these women, they have indeed seen a rapid bone loss and dramatic.
Focused mainly to the hips and spine, osteoporosis has emerged from the first six months of treatment. And it has continued to worsen until the 12 th month, when continued monitoring of these patients…
However, no similar phenomenon in patients whose ovarian function has remained… According to Shapiro "a woman post-menopausal untreated stores usually a bone loss of 1% to 2% per annum. But in our study, they have lost between 4 and 8 times more "...