Osteoporosis

Saturday

Gene Responsible For Osteoporosis, Iceland Discovery

A
team of Icelandic researchers has identified three variants of a gene that could multiply by six the risk of suffering from osteoporosis.

The study was conducted on 1 323 Icelandic belonging to 207 families where cases of osteoporosis were numerous. It has just been published in the journal "PloS Biology."

The results have shown that within the 20 chromosome, the BMP2 gene, which is involved in training and renovation of the bone, would be guilty of an increase between three and six times the risk of osteoporosis.

The researchers then confirmed the link between the BMP2 and disease by studying a group of Danish women after menopause, even if the likelihood of increased risk was lower among them. This discovery could enable the detection of individuals at risk and putting in place mechanisms for prevention.

However, osteoporosis is due to 50% by genetic factors, which themselves are not limited to this gene, and half to external factors. The best way to prevent osteoporosis remains a diet rich in calcium, regular exercise and flee certain habits, like smoking or consumption of certain drugs.

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